Nicam gel contains the active ingredient nicotinamide, which is a form of vitamin B3. It is for the topical treatment of mild to moderate inflammatory acne vulgaris. Nicam Gel is for the topical treatment of mild to moderate inflammatory acne vulgaris. When applied to the skin, it helps to reduce the inflammation and redness of inflammatory acne. This is due to the active ingredient, Nicotinamide, as it has an anti-inflammatory effect. The gel should be applied to the affected area of skin twice daily; however it can take several weeks for the beneficial effects to appear, so it is important to persevere with treatment.